Detalhe da pesquisa
1.
Normalizing granuloma vasculature and matrix improves drug delivery and reduces bacterial burden in tuberculosis-infected rabbits.
Proc Natl Acad Sci U S A
; 121(14): e2321336121, 2024 Apr 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-38530888
2.
Losartan controls immune checkpoint blocker-induced edema and improves survival in glioblastoma mouse models.
Proc Natl Acad Sci U S A
; 120(6): e2219199120, 2023 02 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-36724255
3.
The Angiotensin Antagonist Losartan Modulates Social Reward Motivation and Punishment Sensitivity via Modulating Midbrain-Striato-Frontal Circuits.
J Neurosci
; 43(3): 472-483, 2023 01 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-36639890
4.
Angiotensin II-stimulated proximal nephron superoxide production and fructose-induced salt-sensitive hypertension.
Am J Physiol Renal Physiol
; 326(2): F249-F256, 2024 02 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-38059297
5.
Angiotensin blockade enhances motivational reward learning via enhancing striatal prediction error signaling and frontostriatal communication.
Mol Psychiatry
; 28(4): 1692-1702, 2023 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-36810437
6.
Single nucleotide polymorphism (SNP) rs4291 of the angiotensin-converting enzyme (ACE) gene is associated with the response to losartan treatment in hypertensive patients.
Mol Biol Rep
; 51(1): 458, 2024 Mar 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-38551694
7.
Investigation of Strategies to Block Downstream Effectors of AT1R-Mediated Signalling to Prevent Aneurysm Formation in Marfan Syndrome.
Int J Mol Sci
; 25(9)2024 May 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-38732244
8.
Assembly of In-Situ Gel Containing Nano-Spanlastics of an Angiotensin II Inhibitor as a Novel Epitome for Hypertension Management: Factorial Design Optimization, In-vitro Gauging, Pharmacokinetics, and Pharmacodynamics Appraisal.
AAPS PharmSciTech
; 25(5): 115, 2024 May 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-38755324
9.
Angiotensinergic neurotransmission in the bed nucleus of the stria terminalis is involved in cardiovascular responses to acute restraint stress in rats.
Pflugers Arch
; 475(4): 517-526, 2023 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-36715761
10.
The effects of losartan or angiotensin II receptor antagonists on cartilage: a systematic review.
Osteoarthritis Cartilage
; 31(4): 435-446, 2023 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-36586717
11.
Losartan impairs HTR-8/SVneo trophoblast migration through inhibition of angiotensin II-induced pro-inflammatory profile in human endometrial stromal cells.
Toxicol Appl Pharmacol
; 461: 116383, 2023 02 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-36682589
12.
Losartan alleviates renal fibrosis by inhibiting the biomechanical stress-induced epithelial-mesenchymal transition of renal epithelial cells.
Arch Biochem Biophys
; 748: 109770, 2023 10 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-37783367
13.
Mechanisms underlying the blood pressure-lowering effects of empagliflozin, losartan and their combination in people with type 2 diabetes: A secondary analysis of a randomized crossover trial.
Diabetes Obes Metab
; 25(1): 198-207, 2023 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36089810
14.
Design, synthesis and biological evaluation of novel indole-3-carboxylic acid derivatives with antihypertensive activity.
Bioorg Med Chem Lett
; 90: 129349, 2023 06 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-37236375
15.
Is losartan a promising agent for the treatment of type 1 diabetes-induced testicular germ cell apoptosis in rats?
Mol Biol Rep
; 50(3): 2195-2205, 2023 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-36565418
16.
Altered local RAS in the liver increased the risk of NAFLD in male mouse offspring produced by in vitro fertilization.
BMC Pregnancy Childbirth
; 23(1): 345, 2023 May 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-37173649
17.
Angiotensin-receptor blocker losartan alleviates atrial fibrillation in rats by downregulating frizzled 8 and inhibiting the activation of WNT-5A pathway.
Clin Exp Pharmacol Physiol
; 50(1): 19-27, 2023 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36047789
18.
Losartan in Combination With Bone Marrow Stimulation Showed Synergistic Effects on Load to Failure and Tendon Matrix Organization in a Rabbit Model.
Arthroscopy
; 39(12): 2408-2419, 2023 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-37270113
19.
Editorial Commentary: Bone Marrow Stimulation and Losartan Augmentation of Shoulder Rotator Cuff Repair.
Arthroscopy
; 39(12): 2420-2422, 2023 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-37981385
20.
Metabolomic Profile and Its Correlation with the Plasmatic Levels of Losartan, EXP3174 and Blood Pressure Control in Hypertensive and Chronic Kidney Disease Patients.
Int J Mol Sci
; 24(12)2023 Jun 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-37372980